Title :
Emergence (from chaos?) of regulatory order in the transplanted heart
Author_Institution :
Dept. of Cardiothoracic Surg., Hahnemann Univ., Philadelphia, PA, USA
Abstract :
The principles by which "emergent properties" and functional order of self-organizing system, such as the heart, achieve homeodynamic stability provide a non-reductionist framework for understanding how biological systems adapt to imposed internal and external stresses, i.e., ischemia, organ/tissue replacement. Thus, the newly emergent dynamics of cardiac rhythm arising after heart transplantation may represent a more stable, versatile and adaptive regulatory order.
Keywords :
cardiology; chaos; feedback; nonlinear dynamical systems; physiological models; time series; biological system; cardiac allograft RR-interval time-series; cardiac rhythm; dynamic reorganization; emergence from chaos; external stresses; feedback; functional order; heart rate dynamics; homeodynamic stability; internal stresses; ischemia; nonlinear spatiotemporal interactions; organ/tissue replacement; pointwise correlation dimension; regulatory order; self-organizing system; transplanted heart; Automatic control; Cardiology; Chaos; Control systems; Educational institutions; Heart rate; Heart rate variability; Pacemakers; Rhythm; Surgery;
Conference_Titel :
Engineering in Medicine and Biology Society, 2001. Proceedings of the 23rd Annual International Conference of the IEEE
Print_ISBN :
0-7803-7211-5
DOI :
10.1109/IEMBS.2001.1020504