Selective Manipulation of Superparamagnetic Beads by a Magnetic Microchip

Author

Gooneratne, Chinthaka P. ; Yassine, Omar ; Giouroudi, Ioanna ; Kosel, Jurgen

Author_Institution

King Abdullah Univ. of Sci. & Technol., Thuwal, Saudi Arabia

Volume

49

Issue

7

fYear

2013

fDate

Jul-13

Firstpage

3418

Lastpage

3421

Abstract

In this paper, a magnetic microchip (MMC) is presented, to first trap and then selectively manipulate individual, superparamagnetic beads (SPBs) to another trapping site. Trapping sites are realized through soft magnetic micro disks made of Ni₈₀Fe₂₀, and SPB motion is controlled by current-carrying, tapered, conducting lines made of Au. The MMC was realized using standard microfabrication techniques and provides a cheap and versatile platform for microfluidic systems for cell manipulation.

Keywords

gold; iron alloys; magnetic circuits; microfabrication; microfluidics; nickel alloys; soft magnetic materials; superparamagnetism; Au; MMC; Ni₈₀Fe₂₀; SPB; cell manipulation; conducting lines; current-carrying lines; gold; magnetic microchip; microfabrication; microfluidic systems; soft magnetic microdisks; superparamagnetic beads; tapered lines; trapping site; Charge carrier processes; Magnetic resonance imaging; Magnetic separation; Micromagnetics; Permanent magnets; Saturation magnetization; Soft magnetic materials; Magnetic manipulation; microchip; rare cells; superparamagnetic beads;

fLanguage

English

Journal_Title

Magnetics, IEEE Transactions on

Publisher

ieee

ISSN

0018-9464

Type

jour

DOI

10.1109/TMAG.2013.2244857

Filename

6558917