Model-based 3D object detection from multivariate confocal microscopy images

Author

Wang, Juhui ; Trubuil, Alain ; Graffigne, Christine ; Kaeffer, Bertrand

Author_Institution

Unite de Biometrie, INRA, Jouy-En-Josas, France

Volume

2

fYear

2002

fDate

2002

Abstract

The paper addresses the problem of both prior modeling and object labeling in multivariate microscopy imaging. We make use of a statistical, nonparametric framework to formulate the prior knowledge on microscopy imaging and a model validation technique to achieve the object detection and labeling goal. The approach has been applied in investigations of spatial distribution of nuclei within the colonic glands of rats observed with the help of confocal fluorescence microscopy.

Keywords

biological tissues; biomedical optical imaging; medical image processing; object detection; optical microscopy; statistical analysis; 3D object detection; biomedical research; cell structure; confocal fluorescence microscopy; confocal microscopy images; multivariate microscopy imaging; nonparametric framework; object labeling; prior knowledge; prior modeling; statistical framework; tissue structure; Biomembranes; DNA; Fluorescence; Glands; Labeling; Magnetic resonance imaging; Microscopy; Object detection; Photometry; Tagging;

fLanguage

English

Publisher

ieee

Conference_Titel

Image Processing. 2002. Proceedings. 2002 International Conference on

ISSN

1522-4880

Print_ISBN

0-7803-7622-6

Type

conf

DOI

10.1109/ICIP.2002.1040105

Filename

1040105