• DocumentCode
    3846232
  • Title

    Switch-Matrix-Based High-Density Microelectrode Array in CMOS Technology

  • Author

    Urs Frey;Jan Sedivy;Flavio Heer;Rene Pedron;Marco Ballini;Jan Mueller;Douglas Bakkum;Sadik Hafizovic;Francesca D. Faraci;Frauke Greve;Kay-Uwe Kirstein;Andreas Hierlemann

  • Author_Institution
    Bio Engineering Laboratory, Department of Biosystems Science and Engineering, ETH Zurich, Switzerland
  • Volume
    45
  • Issue
    2
  • fYear
    2010
  • Firstpage
    467
  • Lastpage
    482
  • Abstract
    We report on a CMOS-based microelectrode array (MEA) featuring 11, 011 metal electrodes and 126 channels, each of which comprises recording and stimulation electronics, for extracellular bidirectional communication with electrogenic cells, such as neurons or cardiomyocytes. The important features include: (i) high spatial resolution at (sub)cellular level with 3150 electrodes per mm2 (electrode diameter 7 ?m, electrode pitch 18 ?m); (ii) a reconflgurable routing of the recording sites to the 126 channels; and (iii) low noise levels.
  • Keywords
    "CMOS technology","Microelectrodes","Electrodes","Communication switching","Extracellular","Bidirectional control","Neurons","Cardiology","Spatial resolution","Routing"
  • Journal_Title
    IEEE Journal of Solid-State Circuits
  • Publisher
    ieee
  • ISSN
    0018-9200
  • Type

    jour

  • DOI
    10.1109/JSSC.2009.2035196
  • Filename
    5405139