DocumentCode :
385321
Title :
3D registration of medical scanner volumes and tissue section photographs for evaluation of image-guided treatment
Author :
Lazebnik, R.S. ; Wilson, D.L. ; Breen, M.S. ; Lewin, J.S.
Author_Institution :
Dept. of Biomed. Eng., Case Western Reserve Univ., Cleveland, OH, USA
Volume :
2
fYear :
2002
fDate :
2002
Firstpage :
1007
Abstract :
We created a method for 3D registration of medical scanner image volumes to gross pathology images. We are applying it to evaluate interventional MRI thermal ablation and in vivo localized drug release from a new device, implanted using CT guidance. The method computes an optimum set of rigid body registration parameters by iterative minimization of the Euclidean distances between automatically generated correspondence points, along manually selected fiducial needle paths, and optional point landmarks. Voxel displacement errors depend only on needle localization error when the angle between needles was at least 15 degrees, and the distance objective function is a useful diagnostic for registration quality.
Keywords :
biological tissues; biomedical MRI; biomedical optical imaging; computerised tomography; drug delivery systems; hyperthermia; image registration; iterative methods; medical image processing; photographic applications; radiation therapy; 3D registration; CT guidance; Euclidean distances; correspondence points; gross pathology images; image-guided treatment; in vivo localized drug release; interventional MRI thermal ablation; iterative minimization; medical image processing; medical scanner volumes; rigid body registration parameters; tissue section photographs; voxel displacement errors; Biomedical imaging; Computed tomography; Drugs; In vivo; Iterative methods; Magnetic resonance imaging; Medical diagnostic imaging; Medical treatment; Needles; Pathology;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Engineering in Medicine and Biology, 2002. 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society EMBS/BMES Conference, 2002. Proceedings of the Second Joint
ISSN :
1094-687X
Print_ISBN :
0-7803-7612-9
Type :
conf
DOI :
10.1109/IEMBS.2002.1106249
Filename :
1106249
Link To Document :
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