Title :
Atherosclerotic human carotid bifurcations: mechanical and histological factors
Author :
Kaazempur-Mofrad, M. ; Isasi, A. ; Younis, H. ; Chan, R. ; Hinton, D. ; Sukhova, G. ; Kamm, R.
Abstract :
3D finite element analyses were conducted of the diseased carotid bifurcation using reconstructed models based on in vivo MRI geometries and ultrasound velocity measurements. The resulting wall shear stress (WSS) and oscillatory shear index (OSI) distributions were correlated to histological parameters involved in atherogenesis.
Keywords :
biomechanics; biomedical MRI; biomedical ultrasonics; blood vessels; diseases; finite element analysis; physiological models; ultrasonic velocity measurement; 3D finite element analyses; atherogenesis; atherosclerotic human carotid bifurcations; diseased carotid bifurcation; histological factors; histological parameters; in vivo MRI geometries; mechanical factors; medical diagnostic imaging; oscillatory shear index distributions; ultrasound velocity measurements; wall shear stress; Bifurcation; Finite element methods; Geometry; Humans; In vivo; Magnetic resonance imaging; Solid modeling; Stress; Ultrasonic imaging; Velocity measurement;
Conference_Titel :
Engineering in Medicine and Biology, 2002. 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society EMBS/BMES Conference, 2002. Proceedings of the Second Joint
Print_ISBN :
0-7803-7612-9
DOI :
10.1109/IEMBS.2002.1106375