Title :
A silicon micromachined pin for contact droplet printing
Author :
Tsai, Jane ; Kim, Chang Jin CJ
Author_Institution :
Biomed. Eng. Inter-Departmental Program, California Univ., Los Angeles, CA, USA
Abstract :
We report the design and fabrication of a micromachined silicon pin that serves as a contact-printing device. The pins have potential application in the DNA microarray field for small and precise droplet printing onto a solid support. Our goal is to provide an economic solution for better accuracy and repeatability for such applications as DNA and protein printing by using MEMS technology. The test results showed an average droplet size of 16 μm in diameter, compared with over 100 μm for the commercial pins, as well as more consistent droplet sizes.
Keywords :
DNA; arrays; biomedical electronics; micromachining; micromechanical devices; proteins; 16 micron; DNA microarray; DNA printing; DRIE; MEMS technology; Si; accuracy; capillary action; contact droplet printing; deep reactive-ion-etching; fabrication; protein printing; repeatability; silicon micromachined pin; solid support; surface tension; DNA; Design engineering; Fabrication; Micromechanical devices; Pins; Printing; Proteins; Silicon; Solids; Surface tension;
Conference_Titel :
Engineering in Medicine and Biology, 2002. 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society EMBS/BMES Conference, 2002. Proceedings of the Second Joint
Print_ISBN :
0-7803-7612-9
DOI :
10.1109/IEMBS.2002.1106574
