Title :
An in vivo detector for radiolabeled compounds
Author :
Suddarth, S.A. ; Bolick, N.G. ; Wheele, K.T. ; Wargin, B.A. ; Scarantino, C.W. ; Black, R.D.
Author_Institution :
Sicel Technol., Morrisville, NC, USA
Abstract :
Sicel Technologies has developed an in vivo detector for 14C labeled compounds. Initial studies in rats have been completed in which labeled 2-deoxyglucose and 5-fluoruracil have been monitored dynamically in both tumors and normal tissue. These results are discussed in the context of monitoring tumor metabolism and chemotherapeutic drug uptake.
Keywords :
biomedical equipment; carbon; particle detectors; patient monitoring; radioactive tracers; tumours; 5-fluoruracil; 14C labeled compounds; C; Sicel Technologies; chemotherapeutic drug uptake; initial rat studies; labeled 2-deoxyglucose; normal tissue; tumor metabolism monitoring; Biochemistry; Detectors; In vivo; Medical treatment; Monitoring; Neoplasms; Photomultipliers; Pollution measurement; Probes; Rats;
Conference_Titel :
Engineering in Medicine and Biology, 2002. 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society EMBS/BMES Conference, 2002. Proceedings of the Second Joint
Print_ISBN :
0-7803-7612-9
DOI :
10.1109/IEMBS.2002.1106629
