Title :
Single cell micromanipulation using magnetic beads: a computational model
Author :
Karcher, H. ; Kaazempur-Mofrad, M.R. ; Kamm, R.D.
Author_Institution :
Dept. of Mech. Eng., MIT, Cambridge, MA, USA
Abstract :
A computational finite element model (FEM) model is developed for cell micromanipulation by magnetocytometry. The model provides a robust tool for analysis of detailed strain/stress fields induced in the cell monolayer. Correlation of the computational model and experimental findings promises to shed light on the mechanical properties of the cell and their variation under different mechanical/biological stimulations.
Keywords :
biological techniques; biomagnetism; biomechanics; cellular biophysics; finite element analysis; monolayers; physiological models; biological stimulation; cell mechanical properties; cell mechanics; cell monolayer; detailed strain/stress fields; finite element model; magnetic beads; magnetocytometry; mechanical stimulation; single cell micromanipulation; Biological system modeling; Biology computing; Cells (biology); Computational modeling; Finite element methods; Magnetic analysis; Magnetic field induced strain; Mechanical factors; Robustness; Stress;
Conference_Titel :
Engineering in Medicine and Biology, 2002. 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society EMBS/BMES Conference, 2002. Proceedings of the Second Joint
Print_ISBN :
0-7803-7612-9
DOI :
10.1109/IEMBS.2002.1136854
