Title :
Robustness analysis of a self-oscillating molecular network in Dictyostelium discoideum
Author :
Ma, Lan ; Iglesias, Pablo
Author_Institution :
Dept. of Electr. & Comput. Eng., Johns Hopkins Univ., Laurel, MD, USA
Abstract :
Robustness is an important feature of biochemical systems. We investigate the parametric robustness of a model of self-oscillating network in Dictyostelium discoideum. Robustness to single parameter perturbations is studied through bifurcation theory. Multiparametric robustness is studied using structured singular value (μ) analysis.
Keywords :
bifurcation; biochemistry; biocontrol; control system CAD; control system analysis computing; molecular biophysics; oscillations; physiological models; proteins; robust control; bifurcation theory; biochemical systems; dictyostelium discoideum; multiparametric robustness; parametric robustness; robustness analysis; self-oscillating molecular network; single parameter perturbations; structured singular value analysis; Bifurcation; Biochemical analysis; Biochemistry; Computer networks; Electronic mail; Intelligent networks; Kinetic theory; Proteins; Robust stability; Robustness;
Conference_Titel :
Decision and Control, 2002, Proceedings of the 41st IEEE Conference on
Print_ISBN :
0-7803-7516-5
DOI :
10.1109/CDC.2002.1184219
