Title :
Load balancing: a case study of a pharmaceutical drug candidate database
Author :
Miled Z, B. ; Li, S. ; Martin, J. ; Balagoplakrishna, C. ; Bukhres, O. ; Oppelt, R.J.
Author_Institution :
Dept. of Electr. & Comp. Eng., Indiana Univ., Indianapolis, IN, USA
Abstract :
In the past decade chemical and biological laboratory experiments have generated an explosive amount of data. As a result, a set applications that manipulate these dynamic, heterogeneous and massive amounts of data have emerged. An example of such applications in the pharmaceutical industry is the computational process involved in the early drug discovery of lead drug candidates for a given target disease. The discovery of lead drug candidates requires both consecutive and random data access to the pharmaceutical drug candidate database. This paper focuses on performance enhancement techniques for the pharmaceutical drug candidate database application. In particular, this paper compares static load balancing and dynamic load balancing in the context of the drug candidate database application. This database application is based on multi-queries. Some of these queries are multi-join queries.
Keywords :
database management systems; diseases; medical computing; patient treatment; biological laboratory experiments; chemical laboratory experiments; computational process; dynamic load balancing; early drug discovery; lead drug candidates; multi-queries; pharmaceutical drug candidate database; pharmaceutical industry; random data access; static load balancing; target disease; Biology computing; Chemicals; Computer industry; Databases; Drugs; Explosives; Laboratories; Load management; Manipulator dynamics; Pharmaceuticals;
Conference_Titel :
Bioinformatics and Bioengineering, 2003. Proceedings. Third IEEE Symposium on
Print_ISBN :
0-7695-1907-5
DOI :
10.1109/BIBE.2003.1188973