Title :
A disposable plastic biochip cartridge with on-chip power sources for blood analysis
Author :
Choi, Jin-Woo ; Puntambekar, Aniruddha ; Hong, Chien-Chong ; Chuan Gao ; Zhu, Xiaoshan ; Trichur, Ramachandran ; Han, Jungyoup ; Chilukuru, Srikanth ; Dutta, Madhulika ; Murugesan, Suresh ; Kim, Sanghyo ; Sohn, Young-Soo ; Nevin, Joseph H. ; Beaucage, Gre
Author_Institution :
Dept. of Electr. & Comput. Eng. & Comput. Sci., Cincinnati Univ., OH, USA
Abstract :
This paper presents the development of a disposable plastic biochip with embedded on-chip power sources and integrated biosensor array for applications in clinical diagnostics and point-of-care systems. A cartridge type disposable plastic biochip has been successfully developed and demonstrated for precise sample volume control with smart microfluidic manipulation without costly on-chip active microfluidic components. In addition, the disposable plastic biochip has successfully been tested for the measurements of partial oxygen concentration, glucose, and lactate level in human blood using an integrated biosensor array.
Keywords :
biomedical measurement; biosensors; blood; microfluidics; micromechanical devices; patient diagnosis; blood analysis; clinical diagnostics; disposable plastic biochip cartridge; glucose; human blood; integrated biosensor array; lactate level; on-chip power sources; partial O concentration; point-of-care systems; smart microfluidic manipulation; Biosensors; Blood; Control systems; Diseases; Humans; Microfluidics; Plastics; Sugar; System-on-a-chip; Valves;
Conference_Titel :
Micro Electro Mechanical Systems, 2003. MEMS-03 Kyoto. IEEE The Sixteenth Annual International Conference on
Print_ISBN :
0-7803-7744-3
DOI :
10.1109/MEMSYS.2003.1189782
