A disposable plastic biochip cartridge with on-chip power sources for blood analysis

Author

Choi, Jin-Woo ; Puntambekar, Aniruddha ; Hong, Chien-Chong ; Chuan Gao ; Zhu, Xiaoshan ; Trichur, Ramachandran ; Han, Jungyoup ; Chilukuru, Srikanth ; Dutta, Madhulika ; Murugesan, Suresh ; Kim, Sanghyo ; Sohn, Young-Soo ; Nevin, Joseph H. ; Beaucage, Gre

Author_Institution

Dept. of Electr. & Comput. Eng. & Comput. Sci., Cincinnati Univ., OH, USA

fYear

2003

fDate

19-23 Jan. 2003

Firstpage

447

Lastpage

450

Abstract

This paper presents the development of a disposable plastic biochip with embedded on-chip power sources and integrated biosensor array for applications in clinical diagnostics and point-of-care systems. A cartridge type disposable plastic biochip has been successfully developed and demonstrated for precise sample volume control with smart microfluidic manipulation without costly on-chip active microfluidic components. In addition, the disposable plastic biochip has successfully been tested for the measurements of partial oxygen concentration, glucose, and lactate level in human blood using an integrated biosensor array.

Keywords

biomedical measurement; biosensors; blood; microfluidics; micromechanical devices; patient diagnosis; blood analysis; clinical diagnostics; disposable plastic biochip cartridge; glucose; human blood; integrated biosensor array; lactate level; on-chip power sources; partial O concentration; point-of-care systems; smart microfluidic manipulation; Biosensors; Blood; Control systems; Diseases; Humans; Microfluidics; Plastics; Sugar; System-on-a-chip; Valves;

fLanguage

English

Publisher

ieee

Conference_Titel

Micro Electro Mechanical Systems, 2003. MEMS-03 Kyoto. IEEE The Sixteenth Annual International Conference on

ISSN

1084-6999

Print_ISBN

0-7803-7744-3

Type

conf

DOI

10.1109/MEMSYS.2003.1189782

Filename

1189782