DocumentCode :
393028
Title :
Ultrasonic temperature imaging for the guidance of thermal ablation therapies: in vitro results
Author :
Miller, Naomi R. ; Bamber, Jeffrey C. ; Haar, G.R.
Author_Institution :
Joint Dept. of Phys., R. Marsden Hosp., Sutton, UK
Volume :
2
fYear :
2002
fDate :
8-11 Oct. 2002
Firstpage :
1365
Abstract :
Ultrasonic estimation of heat-induced echo strain has been suggested as a technique for the guidance of thermal ablation tumour therapies by predicting the location of the thermal lesion before it is formed. Preliminary investigations of this method were carried out using in vitro bovine liver starting at a baseline temperature of 24°C. Three non-ablative temperature rises (∼10, 20 and 30°C respectively) were induced using a focused ultrasound surgery system. In each case, a strain (temperature) image was generated by processing ultrasound images acquired before and after tissue heating. The final step was to induce an ablative temperature rise (∼40°C) so as to produce a thermal lesion. The temperature images for all three non-ablative temperature rises possessed excellent spatial and contrast resolution. The technique demonstrated good repeatability within and between tissue samples. The position of the hot spot in the temperature images correlated well with the region of echo enhancement seen in B-mode images after ablation. We conclude that the proposed technique is feasible in the liver, although additional sources of error that will arise in vivo may require correction.
Keywords :
biomedical measurement; biomedical ultrasonics; liver; patient treatment; temperature measurement; tumours; ultrasonic effects; ultrasonic measurement; 10 degC; 20 degC; 24 degC; 30 degC; 40 degC; focused ultrasound surgery system; heat-induced echo strain; in vitro bovine liver; thermal ablation therapies; thermal ablation tumour therapies; thermal lesion; tissue heating; ultrasonic temperature imaging; Bovine; Capacitive sensors; Focusing; In vitro; Lesions; Liver; Medical treatment; Temperature; Tumors; Ultrasonic imaging;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Ultrasonics Symposium, 2002. Proceedings. 2002 IEEE
ISSN :
1051-0117
Print_ISBN :
0-7803-7582-3
Type :
conf
DOI :
10.1109/ULTSYM.2002.1192549
Filename :
1192549
Link To Document :
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