Title :
Processing of neural activity in the human subthalamus in Parkinson´s disease: movement-related and pharmacological modulation
Author :
Priori, A. ; Foffani, G. ; Bianchi, A.M. ; Baselli, G. ; Cerutti, S.
Author_Institution :
Dept. of Biomed. Eng., Politecnico di Milano, Italy
Abstract :
Electrodes for Deep Brain Stimulation offer the unique opportunity to record neural activity from the basal ganglia and to study their pathophysiology in living humans. Using time-frequency analysis techniques it is possible to evaluate the dependence of the spectral properties of human basal ganglia signals (1) on voluntary movement and (2) on drug administration. In this paper some of the results obtained by our group are reviewed and discussed.
Keywords :
bioelectric potentials; biomedical electrodes; diseases; electroencephalography; medical signal processing; microelectrodes; neurophysiology; surgery; time-frequency analysis; EEG activity; Parkinson´s disease; basal ganglia signals; deep brain stimulation electrodes; digital signal processing; drug administration; local field potentials; subcutaneous pacemaker; subthalamic nucleus; surface EMG signal; surgical treatment; time-frequency analysis; voluntary movement; Basal ganglia; Brain stimulation; Drugs; Electrodes; Humans; Medical treatment; Parkinson´s disease; Satellite broadcasting; Surgery; Time frequency analysis;
Conference_Titel :
Neural Engineering, 2003. Conference Proceedings. First International IEEE EMBS Conference on
Print_ISBN :
0-7803-7579-3
DOI :
10.1109/CNE.2003.1196867
