Title :
DNA spot extraction via grayscale range quantization and morphological measurement
Author :
Nakamura, Eric ; Ooura, T. ; Okuizumi, H. ; Sawada, Katsutoshi
Author_Institution :
Dept. of Inf. Networks Eng., Aichi Inst. of Technol., Toyota, Japan
Abstract :
This paper presents a DNA spot extraction algorithm by grayscale range quantization and measuring morphological features or a shape index of DNA spot candidate regions. Due to fuzzy boundaries of DNA spots and intensity variations of background regions in RLGS profile images, extracting DNA spots is a very challenging task. The developed algorithm first obtains DNA spot candidate regions by quantizing the intensity values of a RLGS profile image. The following elimination process of false DNA spots is done by computing and thresholding the shape index.
Keywords :
DNA; feature extraction; mathematical morphology; medical image processing; DNA spot candidate regions; DNA spot extraction algorithm; RLGS profile images; background regions intensity variations; fuzzy boundaries; grayscale range quantization; morphological measurement; shape index thresholding; Biochemistry; Bioinformatics; DNA; Data mining; Electrokinetics; Genomics; Gray-scale; Quantization; Sequences; Shape measurement;
Conference_Titel :
Image Processing, 2003. ICIP 2003. Proceedings. 2003 International Conference on
Print_ISBN :
0-7803-7750-8
DOI :
10.1109/ICIP.2003.1247025
