DNA spot extraction via grayscale range quantization and morphological measurement

Author

Nakamura, Eric ; Ooura, T. ; Okuizumi, H. ; Sawada, Katsutoshi

Author_Institution

Dept. of Inf. Networks Eng., Aichi Inst. of Technol., Toyota, Japan

Volume

1

fYear

2003

fDate

14-17 Sept. 2003

Abstract

This paper presents a DNA spot extraction algorithm by grayscale range quantization and measuring morphological features or a shape index of DNA spot candidate regions. Due to fuzzy boundaries of DNA spots and intensity variations of background regions in RLGS profile images, extracting DNA spots is a very challenging task. The developed algorithm first obtains DNA spot candidate regions by quantizing the intensity values of a RLGS profile image. The following elimination process of false DNA spots is done by computing and thresholding the shape index.

Keywords

DNA; feature extraction; mathematical morphology; medical image processing; DNA spot candidate regions; DNA spot extraction algorithm; RLGS profile images; background regions intensity variations; fuzzy boundaries; grayscale range quantization; morphological measurement; shape index thresholding; Biochemistry; Bioinformatics; DNA; Data mining; Electrokinetics; Genomics; Gray-scale; Quantization; Sequences; Shape measurement;

fLanguage

English

Publisher

ieee

Conference_Titel

Image Processing, 2003. ICIP 2003. Proceedings. 2003 International Conference on

ISSN

1522-4880

Print_ISBN

0-7803-7750-8

Type

conf

DOI

10.1109/ICIP.2003.1247025

Filename

1247025