Title :
Polarimetric imaging of SHG light for spatial distribution measurement of collagen orientation in biological tissue
Author :
Yasui, T. ; Shimabayashi, K. ; Tohno, Y. ; Araki, T.
Author_Institution :
Graduate Sch. of Eng. Sci., Osaka Univ., Japan
Abstract :
We propose a new optical method to indicate distribution of structural orientation of the collagen in biological tissue. This method is based on a two-dimensional imaging of collagen-induced second-harmonic-generation (SHG) light. To evaluate the proposed system, collagen distribution profiles in several human tissues are examined.
Keywords :
biological tissues; biomedical optical imaging; optical harmonic generation; polarimetry; proteins; spatial variables measurement; SHG light; biological tissue; collagen distribution profiles; collagen structural orientation; collagen-induced second-harmonic-generation light; human tissues; polarimetric imaging; spatial distribution measurement; two-dimensional imaging; Biological tissues; Biomedical optical imaging; Humans; Nonlinear optics; Optical harmonic generation; Optical imaging; Optical polarization; Optical scattering; Optical sensors; Tendons;
Conference_Titel :
Lasers and Electro-Optics, 2003. CLEO/Pacific Rim 2003. The 5th Pacific Rim Conference on
Print_ISBN :
0-7803-7766-4
DOI :
10.1109/CLEOPR.2003.1274814
