Title :
Multiharmonic generation biopsy of skin
Author :
Chen, Cheng-Chi ; Chu, Shi-Wei ; Chen, I-Hsiu ; Sun, Chi-Kuang ; Chen, Yung-Chih ; Lin, Bai-Ling
Author_Institution :
Graduate Inst. of Electro-Opt. Eng., Nat. Taiwan Univ., Taipei, Taiwan
Abstract :
Avoiding the on-focus photodamage and phototoxicity problem of two-photon-fluorescence excitation, harmonic generation biopsy based on a ∼1300 nm light source provides a truly noninvasive and highly penetrative optical sectioning of skin.
Keywords :
bio-optics; chromium; fluorescence; high-speed optical techniques; laser applications in medicine; magnesium compounds; optical harmonic generation; photoexcitation; silicon compounds; skin; two-photon processes; 1300 nm; Mg2SiO4:Cr; highly penetrative optical skin sectioning; multiharmonic generation skin biopsy; noninvasive optical skin sectioning; on-focus photodamage; phototoxicity problem; two-photon-fluorescence excitation; Biomedical optical imaging; Biopsy; Ear; Mice; Nonlinear optics; Optical attenuators; Optical harmonic generation; Optical scattering; Skin; Ultrafast optics;
Conference_Titel :
Lasers and Electro-Optics, 2003. CLEO/Pacific Rim 2003. The 5th Pacific Rim Conference on
Print_ISBN :
0-7803-7766-4
DOI :
10.1109/CLEOPR.2003.1274815
