Title :
3D finite element complex domain numerical models of electric fields in blood and myocardium
Author :
Wei, Chia-Ling ; Valvano, Jonathan W. ; Feldman, Marc D. ; Nahrendorf, Matthias ; Pearce, John A.
Author_Institution :
Dept. of Electr. & Comput. Eng., Texas Univ., Austin, TX, USA
Abstract :
The conductance catheter system is a tool to determine left ventricular (LV) volume in vivo. However, the accuracy of this method is limited by three assumptions of the equation to convert conductance to volume: the assumed homogeneity of electric field within LV, myocardium having resistive and not capacitive properties, and assumed constant parallel myocardial conductance. This study investigates weaknesses of these three assumptions. It proposes an equivalent circuit model for mouse LV as well as a calculation method for conductance and capacitance of LV. Furthermore, this study also demonstrates the importance of phase measurement in vivo experiments.
Keywords :
bioelectric phenomena; biomedical MRI; blood; capacitance; catheters; electric admittance; electric resistance; electrocardiography; finite element analysis; phase measurement; 3D finite element complex domain numerical models; blood; capacitance; conductance catheter system; constant parallel myocardial conductance; electric fields; equivalent circuit model; left ventricular volume; mouse left ventricle; myocardium; phase measurement; resistive properties; Blood; Capacitance; Catheters; Equations; Equivalent circuits; Finite element methods; In vivo; Mice; Myocardium; Numerical models;
Conference_Titel :
Engineering in Medicine and Biology Society, 2003. Proceedings of the 25th Annual International Conference of the IEEE
Print_ISBN :
0-7803-7789-3
DOI :
10.1109/IEMBS.2003.1279509