DocumentCode :
406561
Title :
Extraction of action potential waveform from summed neural signals
Author :
Silva, R. ; Zook, J. ; Gaumond, R.
Author_Institution :
Pennsylvania State Univ., University Park, PA, USA
Volume :
2
fYear :
2003
fDate :
17-21 Sept. 2003
Firstpage :
1917
Abstract :
We consider the problem of interpreting the signal recorded from an electrode, which sums currents from a large number of neurons responding asynchronously to an applied stimulus. We use a markov chain numerical simulation to establish conditions under which the action potential waveform can be extracted from the autocorrelation of the summed signal, by means of the Levinson algorithm. We tested the efficacy of the algorithm in recovering the signal for two different action potential (AP) waveforms under different test conditions. We conclude that our system is both capable of recovering the average AP and detecting changes in its morphology.
Keywords :
bioelectric potentials; neurophysiology; numerical analysis; physiological models; Levinson algorithm; action potential waveform; field potential; multiple neuron; summed neural signal; Conductivity; Data mining; Electrodes; Extracellular; Morphology; Neurons; Numerical simulation; Shape; Testing; Voltage;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Engineering in Medicine and Biology Society, 2003. Proceedings of the 25th Annual International Conference of the IEEE
ISSN :
1094-687X
Print_ISBN :
0-7803-7789-3
Type :
conf
DOI :
10.1109/IEMBS.2003.1279800
Filename :
1279800
Link To Document :
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