DocumentCode
406561
Title
Extraction of action potential waveform from summed neural signals
Author
Silva, R. ; Zook, J. ; Gaumond, R.
Author_Institution
Pennsylvania State Univ., University Park, PA, USA
Volume
2
fYear
2003
fDate
17-21 Sept. 2003
Firstpage
1917
Abstract
We consider the problem of interpreting the signal recorded from an electrode, which sums currents from a large number of neurons responding asynchronously to an applied stimulus. We use a markov chain numerical simulation to establish conditions under which the action potential waveform can be extracted from the autocorrelation of the summed signal, by means of the Levinson algorithm. We tested the efficacy of the algorithm in recovering the signal for two different action potential (AP) waveforms under different test conditions. We conclude that our system is both capable of recovering the average AP and detecting changes in its morphology.
Keywords
bioelectric potentials; neurophysiology; numerical analysis; physiological models; Levinson algorithm; action potential waveform; field potential; multiple neuron; summed neural signal; Conductivity; Data mining; Electrodes; Extracellular; Morphology; Neurons; Numerical simulation; Shape; Testing; Voltage;
fLanguage
English
Publisher
ieee
Conference_Titel
Engineering in Medicine and Biology Society, 2003. Proceedings of the 25th Annual International Conference of the IEEE
ISSN
1094-687X
Print_ISBN
0-7803-7789-3
Type
conf
DOI
10.1109/IEMBS.2003.1279800
Filename
1279800
Link To Document