Experiment result and the evaluation in block paradigm and single paradigm

Author

Takeuchi, Yusuke ; Tachibana, Jun ; Yamamoto, Kaori ; Uchida, Kenya ; Yanasima, Kenji ; Maeno, Masato ; Uchiyama, Akihiko ; Magatani, K.

Author_Institution

Dept. of Electr. Eng., Tokai Univ., Tokyo, Japan

Volume

1

fYear

2003

fDate

17-21 Sept. 2003

Firstpage

951

Abstract

Many researchers are investigating the brain function by using a block paradigm in fMRI measurement. However, there are some problems to pick up the activating area of brain for visual stimulation in analysis system which is equipped with MRI normally. It becomes a standard so that using the analysis software such as SPM may deal with such various problems. But, problems exist even if these software are used. Then, we advocate constructing a single paradigm which is a new measurement technique for considering BOLD effect, and specify a target part simply by using fMRI. We compared the ordinary block paradigm to the single paradigm through the aspect of the evaluation of the activating part in the MRI image and the change in the signal intensity (change of hemodynamics).

Keywords

biomedical MRI; blood; brain; haemodynamics; medical image processing; neurophysiology; BOLD effect; block paradigm; blood oxygen dependent level; brain function; fMRI measurement; functional magnetic resonance imaging; hemodynamics; signal intensity; single paradigm; visual stimulation; Delay effects; Electric variables measurement; Hemodynamics; Laboratories; Magnetic field measurement; Magnetic resonance imaging; Measurement techniques; Scanning probe microscopy; Software standards; Time series analysis;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2003. Proceedings of the 25th Annual International Conference of the IEEE

ISSN

1094-687X

Print_ISBN

0-7803-7789-3

Type

conf

DOI

10.1109/IEMBS.2003.1279924

Filename

1279924