Title :
Experiment result and the evaluation in block paradigm and single paradigm
Author :
Takeuchi, Yusuke ; Tachibana, Jun ; Yamamoto, Kaori ; Uchida, Kenya ; Yanasima, Kenji ; Maeno, Masato ; Uchiyama, Akihiko ; Magatani, K.
Author_Institution :
Dept. of Electr. Eng., Tokai Univ., Tokyo, Japan
Abstract :
Many researchers are investigating the brain function by using a block paradigm in fMRI measurement. However, there are some problems to pick up the activating area of brain for visual stimulation in analysis system which is equipped with MRI normally. It becomes a standard so that using the analysis software such as SPM may deal with such various problems. But, problems exist even if these software are used. Then, we advocate constructing a single paradigm which is a new measurement technique for considering BOLD effect, and specify a target part simply by using fMRI. We compared the ordinary block paradigm to the single paradigm through the aspect of the evaluation of the activating part in the MRI image and the change in the signal intensity (change of hemodynamics).
Keywords :
biomedical MRI; blood; brain; haemodynamics; medical image processing; neurophysiology; BOLD effect; block paradigm; blood oxygen dependent level; brain function; fMRI measurement; functional magnetic resonance imaging; hemodynamics; signal intensity; single paradigm; visual stimulation; Delay effects; Electric variables measurement; Hemodynamics; Laboratories; Magnetic field measurement; Magnetic resonance imaging; Measurement techniques; Scanning probe microscopy; Software standards; Time series analysis;
Conference_Titel :
Engineering in Medicine and Biology Society, 2003. Proceedings of the 25th Annual International Conference of the IEEE
Print_ISBN :
0-7803-7789-3
DOI :
10.1109/IEMBS.2003.1279924
