Functional image on glucose metabolism in brain using PET with short time scan

Author

Kimura, Yuichi ; Takabayashi, Yuki ; Oda, Keiichi ; Ishii, Kenji ; Ishiwata, Koichi

Author_Institution

Positron Medical Center, Tokyo Metropolitan Inst. of Gerontology, Japan

Volume

1

fYear

2003

fDate

17-21 Sept. 2003

Firstpage

967

Abstract

Dynamic scan in PET has powerful capability to visualize various functionalities in a living tissue. But a dynamic scan requires long scan duration, and it is not practical for routine use. In this study, a shortened scan protocol is investigated in case of imaging of glucose metabolism in brain using ¹⁸F-FDG. In ordinary protocol of dynamic PET scan, more than 45 minutes is required. It is found that the first 30 minutes after FDG injection is enough to form a parametric image on glucose metabolism if a statistical clustering algorithm is incorporate to composed the parametric images.

Keywords

biochemistry; brain; medical image processing; organic compounds; positron emission tomography; statistical analysis; ¹⁸F-FDG; PET; brain; dynamic scan; functional image; glucose metabolism; parametric images; statistical clustering algorithm; Biochemistry; Biomedical imaging; Clustering algorithms; Image analysis; Kinetic theory; Plasma measurements; Positron emission tomography; Protocols; Sugar; Visualization;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2003. Proceedings of the 25th Annual International Conference of the IEEE

ISSN

1094-687X

Print_ISBN

0-7803-7789-3

Type

conf

DOI

10.1109/IEMBS.2003.1279928

Filename

1279928