Title :
Functional image on glucose metabolism in brain using PET with short time scan
Author :
Kimura, Yuichi ; Takabayashi, Yuki ; Oda, Keiichi ; Ishii, Kenji ; Ishiwata, Koichi
Author_Institution :
Positron Medical Center, Tokyo Metropolitan Inst. of Gerontology, Japan
Abstract :
Dynamic scan in PET has powerful capability to visualize various functionalities in a living tissue. But a dynamic scan requires long scan duration, and it is not practical for routine use. In this study, a shortened scan protocol is investigated in case of imaging of glucose metabolism in brain using 18F-FDG. In ordinary protocol of dynamic PET scan, more than 45 minutes is required. It is found that the first 30 minutes after FDG injection is enough to form a parametric image on glucose metabolism if a statistical clustering algorithm is incorporate to composed the parametric images.
Keywords :
biochemistry; brain; medical image processing; organic compounds; positron emission tomography; statistical analysis; 18F-FDG; PET; brain; dynamic scan; functional image; glucose metabolism; parametric images; statistical clustering algorithm; Biochemistry; Biomedical imaging; Clustering algorithms; Image analysis; Kinetic theory; Plasma measurements; Positron emission tomography; Protocols; Sugar; Visualization;
Conference_Titel :
Engineering in Medicine and Biology Society, 2003. Proceedings of the 25th Annual International Conference of the IEEE
Print_ISBN :
0-7803-7789-3
DOI :
10.1109/IEMBS.2003.1279928
