Title :
Detection of neuronal connectivity with Gerstein´s gravitational method in neuron assemblies with different firing rates
Author :
Gomez, J.M. ; Espinosa, I.
Author_Institution :
Dept. of Control, Univ. Nacional Autonoma de Mexico, Mexico
Abstract :
The gravitational method consists in modeling assembly neuronal activity as if they were particles placed in a n-dimensional plane, according to a function of charge and the activity of the corresponding neuron. The particles get charged and are attracted by those that are also charged at the same time, this allows to detect simultaneously the existing connectivity. The rates of firing activity in several areas of the brain range form 5 to 6 up to 120 spikes per second in extreme cases. Taking this into account a neuronal circuit has been simulated for two cases. One in which the average firing rate is between 5 and 11, and other where the firing rate is between 30 and 115 spikes per second. To achieve a reasonable detection of connectivity the parameters involved and the charge functions must be selected accordingly to the different firing rates. This paper shows the results of such exercise.
Keywords :
brain; neural nets; neurophysiology; physiological models; Gerstein gravitational method; brain; firing activity; firing rates; n-dimensional plane; neuron assemblies; neuronal activity; neuronal circuit; neuronal connectivity detection; Assembly; Brain modeling; Circuit simulation; Circuit testing; Electrodes; Gravity; Histograms; Laboratories; Neurons; Performance analysis;
Conference_Titel :
Engineering in Medicine and Biology Society, 2003. Proceedings of the 25th Annual International Conference of the IEEE
Print_ISBN :
0-7803-7789-3
DOI :
10.1109/IEMBS.2003.1280461