Title :
Multiphoton endoscopy: optical design and application to in vivo imaging of mammalian hippocampal neurons
Author :
Jung, Juergen C. ; Mehta, Amit D. ; Schnitzer, M.J.
Author_Institution :
Bell Labs., Lucent Technol., Murray Hill, NJ, USA
Abstract :
We introduce minimally invasive multiphoton fluorescence microendoscopes (350-1000 /spl mu/ in diameter) based on compound microlenses. We demonstrate multiphoton endoscopy in live animals by visualizing rodent hippocampal neurons and dendrites.
Keywords :
biomedical optical imaging; dendrites; endoscopes; fluorescence; microlenses; multiphoton processes; neurophysiology; optical design techniques; 350 to 1000 micron; compound microlens; dendrites; in vivo imaging; mammalian hippocampal neuron; minimally invasive multiphoton fluorescence microendoscope; multiphoton endoscopy; optical application; optical design; Animals; Endoscopes; Fluorescence; In vivo; Lenses; Microoptics; Minimally invasive surgery; Neurons; Optical design; Optical imaging;
Conference_Titel :
Lasers and Electro-Optics, 2003. CLEO '03. Conference on
Conference_Location :
Baltimore, MD, USA
Print_ISBN :
1-55752-748-2
