• DocumentCode
    412548
  • Title

    Dynamics of gene expression in an artificial genome

  • Author

    Willadsen, Kai ; Wiles, Janet

  • Author_Institution
    Sch. of Inf. Technol. & Electr. Eng., Queensland Univ., Brisbane, Qld., Australia
  • Volume
    1
  • fYear
    2003
  • fDate
    8-12 Dec. 2003
  • Firstpage
    185
  • Abstract
    Complex systems techniques provide a powerful tool to study the emergent properties of networks of interacting genes. In this study we extract models of genetic regulatory networks from an artificial genome, represented by a sequence of nucleotides, and analyse how variations in the connectivity and degree of inhibition of the extracted networks affects the resulting classes of behaviours. For low connectivity systems were found to be very stable. Only with higher connectivity was a significant occurrence of chaos found. Most interestingly, the peak in occurrence of chaos occurs perched on the edge of a phase transition in the occurrence of attractors.
  • Keywords
    artificial life; chaos; evolutionary computation; genetics; artificial genome; attractors; chaos; complex systems; gene expression dynamics; gene interaction; genetic regulatory networks; low connectivity systems; network properties; nucleotide sequence; phase transition; Bioinformatics; Biological system modeling; Chaos; Data mining; Gene expression; Genetics; Genomics; Grounding; Information technology; Intelligent networks;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Evolutionary Computation, 2003. CEC '03. The 2003 Congress on
  • Print_ISBN
    0-7803-7804-0
  • Type

    conf

  • DOI
    10.1109/CEC.2003.1299573
  • Filename
    1299573