DocumentCode
412556
Title
Phylogenetic trees using evolutionary search: initial progress in extending Gaphyl to work with genetic data
Author
Congdon, Clare Bates ; Septor, Kevin J.
Author_Institution
Dept. of Comput. Sci., Colby Coll., Waterville, ME, USA
Volume
1
fYear
2003
fDate
8-12 Dec. 2003
Firstpage
320
Abstract
Gaphyl is an application of evolutionary algorithms to phylogenetics, an approach used by biologists to investigate evolutionary relationships among organisms. For datasets larger than 20-30 species, exhaustive search is not practical in this domain. Gaphyl uses an evolutionary search mechanism to search the space of possible phylogenetic trees, in an attempt to find the most plausible evolutionary hypotheses, while typical phylogenetic software packages use heuristic search methods. In previous work, Gaphyl has been shown to be a promising approach for searching for phylogenetic trees using data with binary attributes and Wagner parsimony to evaluate the trees. In the work reported here, Gaphyl is extended to work with genetic data. Initial results with this extension further suggest that evolutionary search is a promising approach for phylogenetic work.
Keywords
biology computing; evolutionary computation; genetics; tree searching; trees (mathematics); Gaphyl; Wagner parsimony; binary attributes; datasets; evolutionary algorithm application; evolutionary relationships; evolutionary search; exhaustive search; genetic data; heuristic search method; phylogenetic software package; phylogenetic trees; phylogenetic work; tree evaluation; Application software; Computer science; DNA; Drives; Educational institutions; Evolutionary computation; Genetics; Organisms; Phylogeny; Sequences;
fLanguage
English
Publisher
ieee
Conference_Titel
Evolutionary Computation, 2003. CEC '03. The 2003 Congress on
Print_ISBN
0-7803-7804-0
Type
conf
DOI
10.1109/CEC.2003.1299592
Filename
1299592
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