DocumentCode :
419049
Title :
Parameter optimization of an evolutionary algorithm for RNA structure discovery
Author :
Fogel, Gary B. ; Weekes, Dana G. ; Sampath, Rangarajan ; Ecker, David J.
Author_Institution :
Natural Selection, Inc., La Jolla, CA, USA
Volume :
1
fYear :
2004
fDate :
19-23 June 2004
Firstpage :
607
Abstract :
This paper focuses on the optimization of population and selection parameters of an evolutionary algorithm for similar RNA structure discovery. The effects of population settings such as the number of parents and number of offspring per parent, and method of selection (tournament vs. elitist) on the rate of convergence were investigated relative to a problem with a known RNA structure solution. The results indicate that proper setting of the number of parents and offspring can be used to increase the efficiency of the evolutionary process.
Keywords :
biology computing; convergence; evolutionary computation; genetics; macromolecules; optimisation; RNA structure discovery; evolutionary algorithm; parameter optimization; Bioinformatics; Databases; Drugs; Evolutionary computation; Genomics; Organisms; Phylogeny; RNA; Space exploration; Stability;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Evolutionary Computation, 2004. CEC2004. Congress on
Print_ISBN :
0-7803-8515-2
Type :
conf
DOI :
10.1109/CEC.2004.1330913
Filename :
1330913
Link To Document :
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