Title :
Biomolecular sensor based on optical spectroscopy of single gold nanoparticles
Author :
Raschke, G. ; Franzl, T. ; Kowarik, S. ; Sonnichsen, C. ; Klar, T.A. ; Feldmann, J. ; Nichtl, A. ; Kurzinger, K.
Author_Institution :
Dept. of Phys., Munich Univ., Germany
Abstract :
Light-scattering spectroscopy on single gold nanoparticles is used to detect molecular binding events. We show that our method is able to detect less than 200 molecular binding events under physiological conditions.
Keywords :
gold; light scattering; molecular biophysics; nanoparticles; optical sensors; patient diagnosis; visible spectroscopy; Au; biomolecular sensor; clinical diagnostics; light-scattering spectroscopy; molecular binding events; optical spectroscopy; single gold nanoparticles;
Conference_Titel :
Lasers and Electro-Optics, 2004. (CLEO). Conference on
Conference_Location :
San Francisco, CA
Print_ISBN :
1-55752-777-6
