Title :
The BioCD: A high-sensitivity spinning-disk interferometer for antigen detection
Author :
Varma, M.M. ; Nolte, D.D. ; Inerowicz, H.D. ; Regnier, F.E.
Author_Institution :
Dept. of Phys., Purdue Univ., West Lafayette, IN, USA
Abstract :
The BioCD spinning-disk format enables the high-frequency narrow-bandwidth detection of antigen in a high-speed optical immunoassay. We experimentally demonstrate a detection limit approaching 100 attomoles per track and sensitivity to 100 ng/ml.
Keywords :
biological techniques; biotechnology; high-speed optical techniques; light interferometers; molecular biophysics; optical sensors; proteins; BioCD; antigen detection; high-frequency detection; high-sensitivity interferometer; high-speed optical immunoassay; narrow-bandwidth detection; spinning-disk interferometer;
Conference_Titel :
Lasers and Electro-Optics, 2004. (CLEO). Conference on
Conference_Location :
San Francisco, CA
Print_ISBN :
1-55752-777-6
