DocumentCode :
429041
Title :
Blind source separation of nerve cuff recordings
Author :
Tesfayesus, W. ; Yoo, P. ; Moffitt, M. ; Durand, D.M.
Author_Institution :
Dept. of Biomedical Eng., Case Western Reserve Univ., Cleveland, OH, USA
Volume :
1
fYear :
2004
fDate :
1-5 Sept. 2004
Firstpage :
95
Lastpage :
98
Abstract :
Electrical stimulation of peripheral nerves can be used to restore partial motor function to individuals with neurological impairment. Previous work from our lab has shown that the flat interface nerve electrode (FINE) can be used to selectively stimulate fiber populations within a nerve trunk. We expect that selective recording of spatially segregated axon populations may also be possible with the FINE. The purpose of this modeling study was to assess the feasibility of using blind source separation (BSS) of the neurograms recorded with the FINE to distinguish signals from independent fascicles. We show that BSS is useful for identifying independent fascicular signals. Further, we introduce a simple post-BSS processing method that resolves the inherent permutation ambiguity of BSS, and allows the BSS-estimated signals to be deterministically related to the appropriate corresponding fascicles.
Keywords :
bioelectric phenomena; blind source separation; medical signal processing; neurophysiology; physiological models; blind source separation; electrical stimulation; flat interface nerve electrode; nerve cuff recordings; neurograms; neurological impairment; partial motor function; peripheral nerves; spatially segregated axon populations; Biomembranes; Blind source separation; Computer simulation; Electrical stimulation; Electrodes; Gaussian distribution; Independent component analysis; Signal generators; Source separation; Testing; Blind Source Separation; Control Signals; Independent Component Analysis; Nerve Cuff Recordings;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Engineering in Medicine and Biology Society, 2004. IEMBS '04. 26th Annual International Conference of the IEEE
Conference_Location :
San Francisco, CA
Print_ISBN :
0-7803-8439-3
Type :
conf
DOI :
10.1109/IEMBS.2004.1403099
Filename :
1403099
Link To Document :
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