Title :
Tomographic imaging of collagen fiber orientation in human tissue using depth-resolved polarimetry of second-harmonic-generation light
Author :
Sasaki, K. ; Yasui, T. ; Tohno, Y. ; Araki, T.
Author_Institution :
Graduate Sch. of Eng. Sci., Osaka Univ., Japan
Abstract :
We propose a new optical method to indicate cross-sectional profile of the collagen fiber orientation in human tissues. This method is based on depth-resolved polarization measurement of collagen-induced second-harmonic-generation (SHG) light. To evaluate the proposed system, collagen distribution profiles in several human tissues are examined.
Keywords :
biological tissues; optical harmonic generation; optical tomography; polarimetry; proteins; collagen distribution profile; collagen fiber orientation; depth-resolved polarimetry; human tissue; second-harmonic-generation light; tomographic imaging; Biomedical optical imaging; Humans; Laser theory; Optical fiber polarization; Optical harmonic generation; Optical polarization; Optical pumping; Polarimetry; Pump lasers; Tomography;
Conference_Titel :
Biophotonics, 2004. APBP 2004. The Second Asian and Pacific Rim Symposium on
Print_ISBN :
0-7803-8676-0
DOI :
10.1109/APBP.2004.1412353
