Title :
The elastic properties of hamster kidney cells evaluated by ultrasonic atomic force microscopy
Author :
Ebert, Anne M. ; Du, Jikai ; Wang, Xiaowei ; Tittmann, Bernhard
Author_Institution :
Dept. of Eng. Sci. & Mech., Pennsylvania State Univ., University Park, PA, USA
Abstract :
Ultrasonic atomic force microscopy (U-AFM) was used to image the elastic properties of hamster kidney (BHK) cells. Force-distance curves and finite element analysis were also used to assist in the description of the U-AFM images. These tools helped explain the differences in contrast seen from the center to the edge of the cell. The explanation of the U-AFM image contrast will lead to more analytical tools to investigate both non-viable and viable materials.
Keywords :
acoustic microscopy; atomic force microscopy; biomedical ultrasonics; cellular biophysics; finite element analysis; medical image processing; finite element analysis; force-distance curves; hamster kidney cell elastic properties; nonviable materials; ultrasonic atomic force microscopy; viable materials; Atomic force microscopy; Biological cells; Biological materials; Educational institutions; Glass; Image analysis; Mechanical factors; Resonance; Springs; Surface topography;
Conference_Titel :
Ultrasonics Symposium, 2004 IEEE
Print_ISBN :
0-7803-8412-1
DOI :
10.1109/ULTSYM.2004.1417815