Title :
Acoustical characterization of submicron particles of perfluorocarbon in solution [ultrasound targeted contrast agent]
Author :
Couture, O. ; Cherin, E. ; Foster, F.S.
Author_Institution :
Sunnybrook & Women´´s Coll. Health Sci. Centre, Toronto, Ont., Canada
Abstract :
Determining the acoustical properties of submicron particles of perfluorocarbon in solution is important to explain their response to ultrasound pulses when bound to a target. In this study, we present measurements of the frequency-dependent attenuation at different particle sizes, pressures and bandwidths. Backscattering spectra of the particles probed with narrowband pulses at 33 MHz are also shown. This study demonstrates the linearity of submicron particles made of liquid perfluorocarbon at high frequency.
Keywords :
backscatter; biomedical ultrasonics; frequency response; organic compounds; particle size; ultrasonic absorption; ultrasonic scattering; 33 MHz; backscattering spectra; frequency-dependent attenuation; high frequency response linearity; liquid perfluorocarbon; particle size; perfluorocarbon in solution; submicron particle acoustical characterization; submicron particles; target bound perfluorocarbon; tissue/blood contrast; ultrasound pulse response; ultrasound targeted contrast agent; Acoustic measurements; Acoustic pulses; Attenuation measurement; Backscatter; Bandwidth; Frequency measurement; Particle measurements; Size measurement; Ultrasonic imaging; Ultrasonic variables measurement;
Conference_Titel :
Ultrasonics Symposium, 2004 IEEE
Print_ISBN :
0-7803-8412-1
DOI :
10.1109/ULTSYM.2004.1418056
