Title :
A state space approach to noise reduction of 3D fluorescent microscopy images
Author :
Ober, Raimund J. ; Lai, Xuming ; Lin, Zhiping ; Ward, E. Sally
Author_Institution :
Dept. of Electr. Eng., Texas Univ., Dallas, TX, USA
Abstract :
An algorithm is presented to calculate a state space realization of a 3D image set. It is based on interpreting the image set as the impulse response of a 3D separable system. As an application it is shown how the approximation steps, including balanced model reduction methods, in the algorithm can be used to suppress noise in 3D image sets. The approach was motivated by a practical problem in the analysis of 3D fluorescent microscopy image data of fluorescently labelled cells.
Keywords :
estimation theory; image processing; interference suppression; microscopy; smoothing methods; transient response; 3D separable system; balanced model reduction method; fluorescent microscopy image data; fluorescently labelled cell; image set realization; impulse response; noise suppression; state space calculation; Biomedical imaging; Fluorescence; Immune system; Iterative algorithms; Microscopy; Noise reduction; Reduced order systems; Signal processing; Signal processing algorithms; State-space methods;
Conference_Titel :
Image Processing, 2004. ICIP '04. 2004 International Conference on
Print_ISBN :
0-7803-8554-3
DOI :
10.1109/ICIP.2004.1419508
