DocumentCode
434620
Title
Optimal control in a model of dendritic cell transfection cancer immunotherapy
Author
Castiglione, F. ; Piccoli, B.
Author_Institution
Ist. Applicazioni del Calcolo, Consiglio Nazionale delle Ricerche, Rome, Italy
Volume
1
fYear
2004
fDate
17-17 Dec. 2004
Firstpage
585
Abstract
We build a population dynamics model of the competition among immune system cells and a generic tumor cells. Then, we apply the theory of optimal control to find the optimal schedule of injection of autologous dendritic cells used as immunotherapeutic agent.
Keywords
cancer; cellular biophysics; optimal control; optimisation; physiological models; tumours; dendritic cell transfection cancer immunotherapy; generic tumor cells; immune system cells; optimal control; population dynamics model; Biological system modeling; Biology computing; Cancer; Cells (biology); Immune system; Mathematical model; Neoplasms; Optimal control; Optimal scheduling; Tumors;
fLanguage
English
Publisher
ieee
Conference_Titel
Decision and Control, 2004. CDC. 43rd IEEE Conference on
Conference_Location
Nassau
ISSN
0191-2216
Print_ISBN
0-7803-8682-5
Type
conf
DOI
10.1109/CDC.2004.1428694
Filename
1428694
Link To Document