Comparative study of microPET® FOCUS and ECAT HRRT PET systems for small rodents imaging

Author

Jan, S. ; Comtat, C. ; Boisgard, R. ; Trébossen, R.

Volume

6

fYear

2004

fDate

16-22 Oct. 2004

Firstpage

3430

Abstract

This work presents a comparison between The ECAT HRRT PET scanner and the microPET® FOCUS 220 system performances for small rodent imaging applications. We show that the resolution is below 2 mm within a diameter of 6 cm with the FOCUS system and it is below 3 mm within a diameter of 12 cm when using the ECAT HRRT. Moreover, the NEC rate peak is 1.7 Mcps at 2.6 mCi for the HRRT and 0.8 Mcps at 4.6 mCi for the FOCUS. Finally, the FOCUS system is clearly more adapted for brain rat imaging and tumor detection for mice imaging. On the other hand, the ECAT HRRT scanner is better suited for rat imaging in the field of pharmaco-kinetic studies.

Keywords

brain; cancer; image resolution; positron emission tomography; tumours; 12 cm; 6 cm; ECAT high resolution research tomograph; NEC rate peak; PET system; brain rat imaging; image resolution; microPET FOCUS 220 system; pharmaco-kinetic studies; rodents imaging; tumor detection; Animals; Focusing; High-resolution imaging; Image reconstruction; Image resolution; Imaging phantoms; Mice; Positron emission tomography; Rodents; Spatial resolution;

fLanguage

English

Publisher

ieee

Conference_Titel

Nuclear Science Symposium Conference Record, 2004 IEEE

ISSN

1082-3654

Print_ISBN

0-7803-8700-7

Electronic_ISBN

1082-3654

Type

conf

DOI

10.1109/NSSMIC.2004.1466624

Filename

1466624