Title :
An Injectable 64 nW ECG Mixed-Signal SoC in 65 nm for Arrhythmia Monitoring
Author :
Yen-Po Chen ; Dongsuk Jeon ; Yoonmyung Lee ; Yejoong Kim ; Zhiyoong Foo ; Inhee Lee ; Langhals, Nicholas B. ; Kruger, Grant ; Oral, Hakan ; Berenfeld, Omer ; Zhengya Zhang ; Blaauw, D. ; Sylvester, Dennis
Author_Institution :
Univ. of Michigan, Ann Arbor, MI, USA
Abstract :
A syringe-implantable electrocardiography (ECG) monitoring system is proposed. The noise optimization and circuit techniques in the analog front-end (AFE) enable 31 nA current consumption while a minimum energy computation approach in the digital back-end reduces digital energy consumption by 40%. The proposed SoC is fabricated in 65 nm CMOS and consumes 64 nW while successfully detecting atrial fibrillation arrhythmia and storing the irregular waveform in memory in experiments using an ECG simulator, a live sheep, and an isolated sheep heart.
Keywords :
CMOS digital integrated circuits; biomedical electronics; electrocardiography; mixed analogue-digital integrated circuits; patient monitoring; system-on-chip; AFE; CMOS process; ECG simulator; analog front-end; arrhythmia monitoring; atrial fibrillation arrhythmia detection; circuit techniques; current 31 nA; digital back-end; digital energy consumption; injectable ECG mixed-signal SoC; irregular waveform; isolated sheep heart; live sheep; minimum energy computation approach; noise optimization; power 64 nW; size 65 nm; syringe-implantable electrocardiography monitoring system; Electrocardiography; Electrodes; Gain; Heart; Impedance; Monitoring; Noise; Analog front-end (AFE); asynchronous logic; capacitive feedback chopper stabilized instrumental amplifier (CCIA); electrocardiography (ECG); fast Fourier transform (FFT); implantable system; kickback noise; minimum energy point (MEP); mm$^{3}$ ;
Journal_Title :
Solid-State Circuits, IEEE Journal of
DOI :
10.1109/JSSC.2014.2364036
