Title :
Single molecule imaging using a highly confined optical field at a triangular aperture
Author :
Molenda, D. ; Fischer, U.C. ; des Francs, G. Colas ; Naber, A.
Author_Institution :
Phys. Inst., Munster Univ., Germany
Abstract :
We demonstrate that scanning near-field optical microscopy based on a probe with a triangular aperture is capable of imaging single fluorescent molecules with an optical resolution of 30 nm. Numerical simulations agree well with experiment.
Keywords :
biological techniques; fluorescence; image resolution; molecular biophysics; near-field scanning optical microscopy; numerical analysis; proteins; highly confined optical field; numerical simulation; optical resolution; proteins; scanning near-field optical microscopy; single fluorescent molecule imaging; triangular aperture; Apertures; Biomedical optical imaging; Fluorescence; Glass; Image resolution; Optical imaging; Optical microscopy; Optical sensors; Probes; Signal resolution;
Conference_Titel :
Quantum Electronics and Laser Science Conference, 2005. QELS '05
Print_ISBN :
1-55752-796-2
DOI :
10.1109/QELS.2005.1548784
