DocumentCode
445830
Title
A simpler Bayesian network model for genetic regulatory network inference
Author
Bastos, Gustavo ; Guimarães, Katia S.
Author_Institution
Center of Informatics, Fed. Univ. of Pernambuco, Recife, Brazil
Volume
1
fYear
2005
fDate
31 July-4 Aug. 2005
Firstpage
304
Abstract
We use Bayesian networks and a nonparametric regression model for inferring genetic regulatory networks. We have used a combination of the Bayesian information criterion (BIC) and a ´voting´ method to pick out the edges of the output graph. Using BIC makes the model simpler than previous ones, still obtaining, however, good results, as shown in our experiments with synthetic data and Saccharomyces cerevisiae cell cycle microarray gene expression data.
Keywords
belief networks; biology computing; genetics; inference mechanisms; nonparametric statistics; regression analysis; Bayesian information criterion; Bayesian network model; Saccharomyces cerevisiae cell cycle microarray gene expression data; genetic regulatory network inference; nonparametric regression model; voting method; Bayesian methods; Boolean functions; Cells (biology); Differential equations; Electronic mail; Gene expression; Genetics; Informatics; Regulators; Voting;
fLanguage
English
Publisher
ieee
Conference_Titel
Neural Networks, 2005. IJCNN '05. Proceedings. 2005 IEEE International Joint Conference on
Print_ISBN
0-7803-9048-2
Type
conf
DOI
10.1109/IJCNN.2005.1555847
Filename
1555847
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