• DocumentCode
    445861
  • Title

    Protein secondary structure prediction with a hybrid RNN/HMM system

  • Author

    Chen, Jinmiao ; Chaudhari, Narendra S.

  • Author_Institution
    Sch. of Comput. Eng., Nanyang Technol. Univ., Singapore
  • Volume
    1
  • fYear
    2005
  • fDate
    31 July-4 Aug. 2005
  • Firstpage
    538
  • Abstract
    In this paper, we propose a hybrid RNN/HMM system for protein secondary structure prediction, where each secondary structure segment is approximated by a second-order recurrent neural network embedded in the state of a segmental hidden Markov model. We evaluate the hybrid system on the RS126 and CB396 sets and obtain promising results.
  • Keywords
    biology computing; hidden Markov models; pattern classification; proteins; recurrent neural nets; CB396; HMM; RNN; RS126; hidden Markov model; protein secondary structure; recurrent neural network; secondary structure segment; Amino acids; Biology computing; Computational biology; Computer networks; Electronic mail; Embedded computing; Hidden Markov models; Protein engineering; Recurrent neural networks; Sequences;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Neural Networks, 2005. IJCNN '05. Proceedings. 2005 IEEE International Joint Conference on
  • Print_ISBN
    0-7803-9048-2
  • Type

    conf

  • DOI
    10.1109/IJCNN.2005.1555888
  • Filename
    1555888