• DocumentCode
    462023
  • Title

    The Effect of UV Irradiation on the Binding of Anticancer Drug Doxorubicin to DNA in the Presence of TiO/sub 2/ Nanoparticles Binding Drug to DNA

  • Author

    Song, Min ; Wang, Xuemei

  • Author_Institution
    Southeast Univ, Nanjing
  • fYear
    2006
  • fDate
    11-14 Dec. 2006
  • Firstpage
    20
  • Lastpage
    23
  • Abstract
    The considerable effect of titanium dioxide (TiO2) nanoparticles and UV irradiation on the biomolecular binding behavior of anticancer drug doxorubicin has been studied by using electrochemical methods. Our observations demonstrate that the combination of nano TiO2 and UV irradiation could facilitate the respective DNA binding affinity of anticancer agent and significantly enhance the detection sensitivity for the relative biomolecular recognition process.
  • Keywords
    DNA; biochemistry; biological effects of ultraviolet radiation; biomolecular effects of radiation; drugs; electrochemical analysis; nanoparticles; pattern recognition; titanium compounds; DNA binding affinity; TiO2; UV irradiation; anticancer drug doxorubicin; biomolecular binding behavior; biomolecular recognition process; electrochemical method; titanium dioxide nanoparticles;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Biomedical and Pharmaceutical Engineering, 2006. ICBPE 2006. International Conference on
  • Conference_Location
    Singapore
  • Print_ISBN
    978-981-05-79
  • Electronic_ISBN
    81-904262-1-4
  • Type

    conf

  • Filename
    4155855
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=462023