Title :
Design and Construction of a Prototype Rotation Modulation Collimator for Near-Field High-Energy Spectroscopic Gamma Imaging
Author :
Sharma, Amy C. ; Tourassi, Georgia D. ; Kapadia, Anuj J. ; Harrawood, Brian P. ; Bender, Janelle E. ; Crowell, Alexander S. ; Kiser, Mathew R. ; Howell, Calvin R. ; Floyd, Carey E., Jr.
Author_Institution :
Dept. of Biomed. Eng., Duke Univ., Durham, NC
fDate :
Oct. 29 2006-Nov. 1 2006
Abstract :
Neutron Stimulated Emission Computed Tomography (NSECT) is being developed for in vivo measurement of the concentration and location of biologically relevant elements. NSECT is a spectroscopic imaging technique whereby the body is illuminated via high-energy neutrons that excite elemental nuclei that then relax through characteristic gamma radiation. This imaging technique requires high-resolution spectroscopy, thereby eliminating the use conventional scintillation gamma cameras. Consequently, high-purity germanium (HPGe) semiconductor detectors are utilized, providing no spatial information. To obtain 2D elemental concentration images, we are adapting high-energy solar spectroscopy technology. A rotating modulation collimator (RMC) consisting of two parallel-slat collimators is placed in front of the detector to modulate the incoming signal in a manner predicted by its geometry. Reconstruction of 2D images is feasible by counting the number of incident gammas at each rotation angle. The challenge is to identify a RMC geometry that allows this method to work in the near-field environment, which has far fewer assumptions and simplifications than the infinite focus of solar imaging. Herein we describe construction of a prototype RMC and experiments conducted with a radioactive Na point source. These experiments verified that the RMC modulates the signal in a manner consistent with its geometric and physical properties.
Keywords :
biomedical imaging; collimators; emission tomography; image reconstruction; semiconductor counters; 2D elemental concentration images; 2D image reconstruction; NSECT; Neutron Stimulated Emission Computed Tomography; biologically relevant elements; gamma radiation relaxation; high energy neutron illumination; high purity germanium semiconductor detectors; high resolution spectroscopy; in vivo concentration measurement; near field RMC geometry; near field high energy spectroscopic gamma imaging; parallel slat collimators; prototype rotation modulation collimator; radioactive sodium point source; spectroscopic imaging technique; Collimators; Geometry; High-resolution imaging; Modular construction; Neutrons; Optical imaging; Prototypes; Solid scintillation detectors; Spectroscopy; Stimulated emission;
Conference_Titel :
Nuclear Science Symposium Conference Record, 2006. IEEE
Conference_Location :
San Diego, CA
Print_ISBN :
1-4244-0560-2
Electronic_ISBN :
1095-7863
DOI :
10.1109/NSSMIC.2006.354310