Optimization of Gated Liver FDG PET with Non-Uniform Respiration

Author

Shilov, M.A. ; Frey, Eric C. ; Segars, W. Paul ; Xu, Jingyan ; Tsui, Benjamin M W

Author_Institution

Div. of Med. Imaging Phys., Johns Hopkins Univ., Baltimore, MD

Volume

4

fYear

2006

fDate

Oct. 29 2006-Nov. 1 2006

Firstpage

2594

Lastpage

2596

Abstract

The objective of this research is to optimize and characterize the respiratory gated reconstruction protocol in liver FDG PET scans with non-uniform respiration using Monte-Carlo simulations. Assuming externally-tracked motion information and NCAT respiratory motion model, we compare the standard time gating and optimized amplitude gating methods. Two spherically shaped liver lesions with FWHM of 1 cm and 2 cm are used to evaluate the accuracy of each method in determining the size and the position of the lesions with GE Discovery LS scanner.

Keywords

Monte Carlo methods; image reconstruction; liver; medical image processing; motion compensation; positron emission tomography; 1 cm; 2 cm; GE Discovery LS scanner; Monte Carlo simulations; NCAT respiratory motion model; externally tracked motion; gated liver FDG PET optimization; lesion position; lesion size; nonuniform respiration; optimized amplitude gating methods; respiratory gated reconstruction protocol; standard time gating; Abdomen; Cancer; Image reconstruction; Imaging phantoms; Lesions; Liver; Positron emission tomography; Protocols; Shape; Signal to noise ratio;

fLanguage

English

Publisher

ieee

Conference_Titel

Nuclear Science Symposium Conference Record, 2006. IEEE

Conference_Location

San Diego, CA

ISSN

1095-7863

Print_ISBN

1-4244-0560-2

Electronic_ISBN

1095-7863

Type

conf

DOI

10.1109/NSSMIC.2006.354438

Filename

4179552