Title :
In Vitro Epileptic Seizure Prediction Microsystem
Author :
Aziz, J. ; Karakiewicz, R. ; Genov, R. ; Chiu, A.W.L. ; Bardakjian, B.L. ; Derchansky, M. ; Carlen, P.L.
Author_Institution :
Dept. of Electr. & Comput. Eng., Toronto Univ., Ont.
Abstract :
The architecture and VLSI implementation of an epileptic seizure prediction microsystem are presented. The microsystem comprises a neural recording interface and a seizure prediction processor. The two functional blocks have been prototyped in a 0.35 mum CMOS technology and experimentally characterized. The integrated microsystem is validated in predicting the onsets of seizures off line in an in vitro epilepsy model of recurrent spontaneous seizures in the hippocampus of mice.
Keywords :
CMOS integrated circuits; VLSI; diseases; micromechanical devices; microprocessor chips; neural nets; 0.35 micron; CMOS technology; VLSI implementation; epileptic seizure prediction microsystem; in vitro epilepsy model; mice hippocampus; neural recording interface; seizure prediction processor; Biomedical engineering; Brain; CMOS technology; Epilepsy; In vitro; Low pass filters; Medical treatment; Neuroscience; Very large scale integration; Voltage;
Conference_Titel :
Circuits and Systems, 2007. ISCAS 2007. IEEE International Symposium on
Conference_Location :
New Orleans, LA
Print_ISBN :
1-4244-0920-9
Electronic_ISBN :
1-4244-0921-7
DOI :
10.1109/ISCAS.2007.378090
