Knowledge Discovery Scientific Workflows in Clinico-Genomics

Author

Potamias, George ; Koumakis, Lefteris ; Kanterakis, Alexandros ; Sfakianakis, Stelios ; Analyti, Anastasia ; Moustakis, Vassilis ; Kafetzopoulos, Dimitris ; Rueping, Stefan ; Tsiknakis, Manolis

Author_Institution

Found. for Res. & Technol., Hellas (FORTH), Heraklion

Volume

1

fYear

2007

fDate

29-31 Oct. 2007

Firstpage

91

Lastpage

95

Abstract

With the completion of the human genome and the entrance into the post-genomic era, translational research rises as a major need. In this paper, we present a knowledge discovery workflow (KDw) and its utilization in the context of clinico-genomic trials. KDw aims towards the discovery of ´evidential´ correlations between patients´ genomic and clinical profiles. Application of KDw on a real-world clinico-genomic (breast cancer) study demonstrates the reliability, efficacy, and efficiency of the approach.

Keywords

data mining; genetics; medical computing; medical information systems; clinico-genomics trial; knowledge discovery scientific workflow; patient genome; Bioinformatics; Data mining; Diseases; Genomics; Laboratories; Management information systems; Mediation; Medical diagnostic imaging; Medical treatment; Risk management;

fLanguage

English

Publisher

ieee

Conference_Titel

Tools with Artificial Intelligence, 2007. ICTAI 2007. 19th IEEE International Conference on

Conference_Location

Patras

ISSN

1082-3409

Print_ISBN

978-0-7695-3015-4

Type

conf

DOI

10.1109/ICTAI.2007.32

Filename

4410268