DocumentCode :
46975
Title :
Real-Time Monitoring of Magnetic Nanoparticles Diffusion in Lateral Flow Microporous Membrane Using Spin Valve Sensors
Author :
Chicharo, A. ; Cardoso, F. ; Cardoso, S. ; Freitas, P.J.P.
Author_Institution :
Inst. de Eng. de Sist. e Comput.-Microsistemas e Nanotecnologias, Lisbon, Portugal
Volume :
51
Issue :
1
fYear :
2015
fDate :
Jan. 2015
Firstpage :
1
Lastpage :
4
Abstract :
This paper investigates real-time monitoring and detection of 10.5 nm magnetic nanoparticles (MNPs) (Fe3O4) flowing in a nitrocellulose (NC) membrane over two spin valve sensors. The fabricated device gives information on the concentration of MNP flowing through the NC membrane of a typical lateral flow test, and gives relevant dynamic characteristics, such as flow rate and MNP distribution on capillary-driven systems. Sensor output varies linearly with MNP concentration. Experiments show average flow rates varying from 0.2 to 0.3 mm/s depending on MNP concentration. Signal shape [V(t)] gives information on MNP spatial distribution at the particle front flowing over the sensor.
Keywords :
iron compounds; magnetic particles; magnetic sensors; membranes; microsensors; nanomagnetics; nanoparticles; nanosensors; porous materials; spin valves; Fe3O4; capillary-driven systems; dynamic characteristics; flow rate; lateral flow microporous membrane; lateral flow test; magnetic nanoparticle diffusion; magnetic nanoparticle spatial distribution; nitrocellulose membrane; real-time monitoring; size 10.5 nm; spin valve sensors; Biomembranes; Magnetic resonance imaging; Nanoparticles; Spin valves; Strips; Lateral flow; magnetic nanoparticles (MNPs); point-of-care; spin valve (SV) sensors;
fLanguage :
English
Journal_Title :
Magnetics, IEEE Transactions on
Publisher :
ieee
ISSN :
0018-9464
Type :
jour
DOI :
10.1109/TMAG.2014.2358645
Filename :
7029207
Link To Document :
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