Title :
Model order selection for quantification of a multi-exponential magnetic resonance spectrum
Author :
Devos, A. ; Bergans, N. ; Dresselaers, T. ; Brabanter, J. De ; Sima, D.M. ; Vanhamme, L. ; Vanstapel, F. ; Hecke, P. Van ; Huffel, S. Van
Author_Institution :
Dept. of Electr. Eng., Katholieke Univ., Leuven
fDate :
Aug. 30 2006-Sept. 3 2006
Abstract :
Magnetic resonance spectroscopic signals analyzed by time-domain models in order to retrieve estimates of the model parameters usually require prior knowledge about the model order. For multi-exponential signals where a superposition of peaks occurs at the same resonance frequency, but with different damping values, model order selection criteria from information theory can be used. In this study, several generalized versions of information criteria are compared using Monte-Carlo simulation signals. The best criterion is further applied for selecting the model order of experimental glycogen signals
Keywords :
Monte Carlo methods; biochemistry; biomedical measurement; liver; magnetic resonance spectroscopy; molecular biophysics; organic compounds; time-domain analysis; Monte-Carlo simulation signal; damping value; glycogen synthesis; information theory; magnetic resonance spectroscopic signal; model parameters estimation; multiexponential magnetic resonance spectrum; perfused liver; resonance frequency; time-domain model; Damping; Liver; Magnetic resonance; Nuclear magnetic resonance; Resonant frequency; Signal analysis; Signal synthesis; Spectroscopy; Sugar; Time domain analysis;
Conference_Titel :
Engineering in Medicine and Biology Society, 2006. EMBS '06. 28th Annual International Conference of the IEEE
Conference_Location :
New York, NY
Print_ISBN :
1-4244-0032-5
Electronic_ISBN :
1557-170X
DOI :
10.1109/IEMBS.2006.260107