Title :
Modeling of the Bioactivated Nanopore Devices
Author :
Talasaz, AmirAli H. ; Liu, Yang ; Ronaghi, Mostafa ; Davis, Ronald W.
Author_Institution :
Dept. of Electr. Eng., Stanford Univ., CA
fDate :
Aug. 30 2006-Sept. 3 2006
Abstract :
This paper presents the modeling of the electrical properties of bioactivated nanopores, customized nanopore devices with a biological macromolecule attached in the pore as the probe. These devices are capable of detecting and analyzing interactions between the attached biomolecule and the molecules in the analyte at a single molecule level
Keywords :
bioelectric phenomena; biological techniques; molecular biophysics; molecular dynamics method; nanotechnology; scanning electron microscopy; bioactivated nanopore device modeling; biological macromolecule; biomolecule; chemical binding; electrical properties; molecular dynamics simulation; scanning secondary electron microscopy; scanning tunnelling electron microscopy; single molecule level; Biological system modeling; Biomembranes; Genomics; Gold; Molecular biophysics; Nanobioscience; Nanoporous materials; Scanning electron microscopy; Silicon; Sputtering;
Conference_Titel :
Engineering in Medicine and Biology Society, 2006. EMBS '06. 28th Annual International Conference of the IEEE
Conference_Location :
New York, NY
Print_ISBN :
1-4244-0032-5
Electronic_ISBN :
1557-170X
DOI :
10.1109/IEMBS.2006.260261
