In-vivo Lung Cancer Imaging in Mice using 360Â° Free-space Fluorescence Molecular Tomography

Author

Deliolanis, Nikolaos ; Lasser, Tobias ; Niedre, Mark ; Soubret, Antoine ; Ntziachristos, Vasilis

Author_Institution

Lab. for Bio-optics & Molecular Imaging, Massachusetts Gen. Hosp., Boston, MA

fYear

2006

fDate

Aug. 30 2006-Sept. 3 2006

Firstpage

2370

Lastpage

2372

Abstract

We present the development and performance characteristics of a free-space fluorescence tomography system. The imaging system can capture complete angle projections of photons propagating through tissue in transillumination using a CCD camera. Experimental data on imaging lung cancer are presented. Overall, this imaging approach can offer unprecedented imaging performance in fluorescence molecular tomography of small animals

Keywords

CCD image sensors; bio-optics; biomedical optical imaging; cancer; fluorescence; lung; molecular biophysics; optical tomography; tumours; CCD camera; angle projections; free-space fluorescence molecular tomography; in-vivo lung cancer imaging; photon propagation; transillumination; Animals; Cancer; Charge coupled devices; Charge-coupled image sensors; Fluorescence; Image reconstruction; Lungs; Mice; Optical imaging; Tomography;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2006. EMBS '06. 28th Annual International Conference of the IEEE

Conference_Location

New York, NY

ISSN

1557-170X

Print_ISBN

1-4244-0032-5

Electronic_ISBN

1557-170X

Type

conf

DOI

10.1109/IEMBS.2006.260683

Filename

4462270