Title :
New Ensemble Machine Learning Method for Classification and Prediction on Gene Expression Data
Author_Institution :
Dept. of Comput. & Informatics, Univ. of Lincoln
fDate :
Aug. 30 2006-Sept. 3 2006
Abstract :
A reliable and precise classification of tumours is essential for successful treatment of cancer. Recent researches have confirmed the utility of ensemble machine learning algorithms for gene expression data analysis. In this paper, a new ensemble machine learning algorithm is proposed for classification and prediction on gene expression data. The algorithm is tested and compared with three popular adopted ensembles, i.e. bagging, boosting and arcing. The results show that the proposed algorithm greatly outperforms existing methods, achieving high accuracy over 12 gene expression datasets
Keywords :
biology computing; cancer; genetics; learning (artificial intelligence); molecular biophysics; pattern classification; tumours; cancer; ensemble machine learning; gene expression data; microarray; tumour classification; Algorithm design and analysis; Bagging; Boosting; Gene expression; Learning systems; Machine learning; Machine learning algorithms; Testing; Training data; Voting; ensemble machine learning; microarray; pattern recognition;
Conference_Titel :
Engineering in Medicine and Biology Society, 2006. EMBS '06. 28th Annual International Conference of the IEEE
Conference_Location :
New York, NY
Print_ISBN :
1-4244-0032-5
Electronic_ISBN :
1557-170X
DOI :
10.1109/IEMBS.2006.259893