Microneedle Array for Measuring Wound Generated Electric Fields

Author

Mukerjee, E.V. ; Isseroff, R.R. ; Nuccitelli, R. ; Collins, S.D. ; Smith, R.L.

Author_Institution

Center for Micro & Nano Technol., Lawrence Livermore Nat. Lab., CA

fYear

2006

fDate

Aug. 30 2006-Sept. 3 2006

Firstpage

4326

Lastpage

4328

Abstract

A microneedle array has been fabricated and applied to the measurement of transdermal skin potentials in human subjects. Potential changes were recorded in the vicinity of superficial wounds, confirming the generation of a lateral electric field in human skin. The measured electric field decays with distance from the wound edge, and is directed towards the wound. The measurement of endogenous fields in skin is a prelude to the study of the therapeutic efficacy of applied electric fields to chronic non-healing wounds

Keywords

bioelectric potentials; biomedical equipment; biomedical measurement; skin; wounds; chronic nonhealing wounds; human skin; microneedle array; superficial wounds; transdermal skin potential; wound generated electric field measurement; Bioelectric phenomena; Biomedical measurements; Electric potential; Electric resistance; Electric variables measurement; Electrical resistance measurement; Humans; Immune system; Skin; Wounds;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2006. EMBS '06. 28th Annual International Conference of the IEEE

Conference_Location

New York, NY

ISSN

1557-170X

Print_ISBN

1-4244-0032-5

Electronic_ISBN

1557-170X

Type

conf

DOI

10.1109/IEMBS.2006.260205

Filename

4462758